藥物詳細合成路線
| Name | Riodoxol | | Chemical Name | 2,4,6-Triiodoresorcine;2,4,6-Triiodo-1,3-benzenediol;2,4,6-Triiodo-1,3-dihydroxybenzene | | CAS | 19403-92-0 | | Related CAS | | | Formula | C6H3I3O2 | | Structure |  | | Formula Weight | 487.80281 | | Stage | 上市-1985 | | Company | All-Russian Chem.-Pharm. Res. Inst. (Originator) | | Activity/Mechanism | Antibacterial Drugs, Antifungal Agents, ANTIINFECTIVE THERAPY, Antiviral Drugs, Dermatologic Drugs | | Syn. Route | 1 | | Route 1 | | the method of synthesis for 2,4,6-triiodoresorcine comprises a stage of resorcin (i) iodination with iodine chloride in the presence of hydrochloric acid as a catalyzer. the reaction mixture is allowed to stand for 1 h at the temperature of 20-5 c. the precipitate is filtered and dried at 50 c. triiodoresorcine yield is 93.6% (crystallized from ccl4). | | |  | | List of intermediates | No. | | [1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-4-isoquinolinyl]methanol | (i) | | | Reference 1: nikolaeva, e.s.; riodoxol. drugs fut 1985, 10, 1, 35. |
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來源:藥化網
作者:藥化小編
摘要:本文合成路線介紹的是藥物中文名2,4,6-三碘間苯二酚；英文名Riodoxol；CAS[19403-92-0]
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